{"id":11,"date":"2019-03-19T18:46:28","date_gmt":"2019-03-19T09:46:28","guid":{"rendered":"http:\/\/sugiyama-lab.bs.teu.ac.jp\/?page_id=11"},"modified":"2026-09-25T11:06:40","modified_gmt":"2026-09-25T02:06:40","slug":"%e7%a0%94%e7%a9%b6%e6%a5%ad%e7%b8%be","status":"publish","type":"page","link":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/?page_id=11","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"

Scientific meetings<\/strong><\/p>\n

2026\u5e74<\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u6a5f\u68b0\u5b66\u7fd2\u3092\u5fdc\u7528\u3057\u305f\u4e73\u764c\u6bdb\u7d30\u8840\u7ba1\u306e\u5f62\u614b\u691c\u51fa\u6cd5\u306e\u958b\u767a\u3000\u7b2c8\u56de\u65e5\u672c\u30e1\u30c7\u30a3\u30ab\u30ebAI\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a<\/p>\n

(2) \u77f3\u5ddd\u885b\u3089\u3000\u7d50\u8178\u304c\u3093\u7d30\u80de\u306e\u7d30\u80de\u5206\u88c2\u6291\u5236\u6d3b\u6027\u3092\u6307\u6a19\u306b\u3057\u305fRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3067\u767a\u898b\u3057\u305fshRNA\u306e\u6a19\u7684\u907a\u4f1d\u5b50\u306e\u89e3\u6790\u3000\u65e5\u672c\u751f\u5316\u5b66\u4f1a2026\u5e74\u5ea6\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

(3) \u52a0\u7d0d\u7384\u6597\u3089\u3000\u7d30\u80de\u8001\u5316RNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3067\u767a\u898b\u3055\u308c\u305fClone6\u306b\u3088\u308bHCT116\u7d30\u80de\u304a\u3088\u3073HT-29\u7d30\u80de\u306e\u8001\u5316\u8a98\u5c0e\u3000\u65e5\u672c\u751f\u5316\u5b66\u4f1a2026\u5e74\u5ea6\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

(4) \u5f35\u3089\u3000NANOG\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u53ef\u8996\u5316\u3092\u76ee\u7684\u3068\u3057\u305f\u86cd\u5149\u30ec\u30dd\u30fc\u30bf\u30fc\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9\u3000\u65e5\u672c\u751f\u5316\u5b66\u4f1a2026\u5e74\u5ea6\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

2025\u5e74<\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u764c\u514d\u75ab\u7d44\u7e54\u5207\u7247\u306e\u8840\u7ba1\u8d70\u884c\u3092\u8b58\u5225\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\u3000\u7b2c77\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(2) Tomoyasu Sugiyama et al. Development of an artificial intelligence system for identification of cancer vessel formation in immunohistochemical image. CBI annual meeting (2024) O01-03<\/p>\n

(3) \u85e4\u6fa4\u822a\u5e73\u3089\u3000\u5e79\u7d30\u80de\u69d8\u306e\u7279\u5fb4\u3092\u8a98\u5c0e\u3057\u305f\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u89e3\u6790\u3000\u7b2c98\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(4) \u6749\u7530\u5c06\u3089\u3000\u304c\u3093\u5e79\u7d30\u80de\u69d8\u306e\u6027\u8cea\u3092\u7372\u5f97\u3057\u305f\u7d50\u8178\u304c\u3093\u7d30\u80de\u306b\u304a\u3051\u308b\u8102\u80aa\u6ef4\u3068\u305d\u306e\u6297\u9178\u5316\u80fd\u306e\u89e3\u6790\u3000\u7b2c98\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(5) \u9752\u6728\u665f\u771e\u3089\u3000HCT116\u7d30\u80de\u3092\u8001\u5316\u8a98\u5c0e\u3055\u305b\u308b\u6709\u529bshRNA\u30af\u30ed\u30fc\u30f3\u306e\u8001\u5316\u8a98\u5c0e\u6027\u8a55\u4fa1 \u7b2c98\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(6) \u7530\u53e3\u611b\u9065\u3089\u3000CoQ10\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50PDSS2\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u305f\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80de\u306e\u6297\u304c\u3093\u5264\u611f\u53d7\u6027\u306e\u89e3\u6790\u3000\u7b2c98\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

2024\u5e74<\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u4e73\u764c\u6bdb\u7d30\u8840\u7ba1\u306e\u7570\u5e38\u3092\u8b58\u5225\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\u3000\u7b2c6\u56de\u65e5\u672c\u30e1\u30c7\u30a3\u30ab\u30ebAI\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a<\/p>\n

(2) \u9f8d\u660a\u3089\u3000\u6c34\u6676\u632f\u52d5\u5b50\u30de\u30a4\u30af\u30ed\u30d0\u30e9\u30f3\u30b9\u6cd5\u3092\u7528\u3044\u305f\u304c\u3093\u7d30\u80de\u306e\u8a55\u4fa1\u304a\u3088\u3073\u6297\u304c\u3093\u5264\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306e\u89e3\u6790\u3000\u7b2c76\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(3) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u764c\u306e\u8840\u7ba1\u8d70\u884c\u3092\u6df1\u5c64\u5b66\u7fd2\u3057\u305f\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\u3000\u7b2c76\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(4) Tomoyasu Sugiyama et al. Deep leaning of new morphological characteristics of blood vessel in breast cancer. CBI annual meeting (2024) O02_01<\/p>\n

(5) \u9752\u6728\u665f\u771e\u3089\u3000HCT116\u7d30\u80de\u3092\u8001\u5316\u8a98\u5c0e\u3055\u305b\u308b\u65b0\u898fshRNA\u306eRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u7b2c97\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(6) \u85e4\u6fa4\u822a\u5e73\u3089\u3000\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u3092\u6d88\u5931\u3055\u305b\u308b\u65b0\u898fshRNA\u306eRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u7b2c97\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(7) \u6749\u7530\u5c06\u3000\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80deHCT116\u306e\u8102\u80aa\u6ef4\u84c4\u7a4d\u306b\u95a2\u3059\u308b\u7d30\u80de\u8a55\u4fa1\u7cfb\u306e\u69cb\u7bc9\u3000\u5927\u5b66\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0\u516b\u738b\u5b50\u7b2c16\u56de\u5b66\u751f\u767a\u8868\u4f1a<\/p>\n

2023<\/em>\u5e74<\/p>\n

(1) \u5c71\u53e3\u97ff\u3089\u3000\u6c34\u6676\u632f\u52d5\u5b50\u30de\u30a4\u30af\u30ed\u30d0\u30e9\u30f3\u30b9\u6cd5\u3068\u753b\u50cf\u89e3\u6790\u306b\u3088\u308b\u7d30\u80de\u8001\u5316\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3000\u7b2c75\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(2) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u4eba\u5de5\u77e5\u80fd\u304c\u8b58\u5225\u3057\u305f\u304c\u3093\u5e79\u7d30\u80de\u3092\u6df1\u5c64\u5b66\u7fd2\u3057\u305f\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\u3000\u7b2c75\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(3) \u82e5\u677e\u97f3\u5b50\u3089\u3000\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50PDSS2\u3092\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3057\u305f\u304c\u3093\u7d30\u80de\u306e\u819c\u9178\u5316\u306e\u89e3\u6790\u3000\u7b2c96\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(4) \u4e38\u5c71\u7adc\u4eba\u3089\u3000\u819c\u30bf\u30f3\u30d1\u30af\u8ceaTMEM117\u306e\u5c0f\u80de\u4f53\u30b9\u30c8\u30ec\u30b9\u3092\u4ecb\u3057\u305f\u6297\u304c\u3093\u4f5c\u7528\u3000\u7b2c96\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a<\/p>\n

2022<\/em>\u5e74<\/p>\n

(1) \u5de5\u85e4\u5eb7\u535a\u3089\u3000\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80de\u682aHCT116\u306eROS\u30ec\u30d9\u30eb\u306e\u5897\u52a0\u3092\u8a98\u5c0e\u3059\u308bshRNA\u306eRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30002022\u5e74\u5ea6 \u65e5\u672c\u751f\u5316\u5b66\u4f1a\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

(2) \u82e5\u677e\u97f3\u5b50\u3089\u3000CoQ\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50PDSS2<\/em>\u306e\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u306b\u3088\u308b\u7d30\u80de\u306e\u819c\u9178\u5316\u306e\u691c\u8a0e\u30002022\u5e74\u5ea6 \u65e5\u672c\u751f\u5316\u5b66\u4f1a\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

(3) \u5ca9\u6c38\u907c\u3089\u3000\u304c\u3093\u7d30\u80de\u5206\u88c2\u3092\u6291\u5236\u3059\u308b\u4eba\u5de5\u6838\u9178\u306eRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c7\u56de\u5e74\u4f1a<\/p>\n

(4) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u6df1\u5c64\u5b66\u7fd2\u6cd5\u3092\u5fdc\u7528\u3057\u305f\u304c\u3093\u5e79\u7d30\u80de\u5f62\u614b\u306e\u8a8d\u8b58\u6280\u8853\u306e\u958b\u767a\u3000\u7b2c45\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2021<\/em>\u5e74<\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3000\u304c\u3093\u5e79\u7d30\u80de\u3092\u8b58\u5225\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u306e\u305f\u3081\u306e\u57fa\u790e\u7814\u7a76\u3000\u30d5\u30a1\u30fc\u30deIT & \u30c7\u30b8\u30bf\u30eb\u30d8\u30eb\u30b9 \u30a8\u30ad\u30b9\u30dd 2021<\/p>\n

(2) Tomoyasu Sugiyama\u3000Segmentation of Cancer Stem Cell using CGAN\u3000IEEE-NANOMED 2021<\/p>\n

2020\u5e74<\/em><\/p>\n

(1) \u5ca9\u6c38\u907c\u3089\u3000RNAi screening for the molecules inhibiting the division of human colon cancer cell line HCT116. \u7b2c43\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2019\u5e74<\/em><\/p>\n

(1) \u4e80\u7530\u5f18\u4e4b\u3089\u3000Conditional Generative Adversarial Nets\u3092\u7528\u3044\u305fiPS\u7d30\u80de\u7531\u6765\u304c\u3093\u5e79\u7d30\u80de\u691c\u51fa \u30b7\u30b9\u30c6\u30e0\u306e\u8a66\u4f5c\u3068\u305d\u306e\u8a55\u4fa1\u3000\u7b2c1\u56de\u30e1\u30c7\u30a3\u30ab\u30ebAI\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a<\/p>\n

(2) \u6e21\u9089\u82f1\u660e\u3089\u3000TMEM117\u3068GFP\u306e\u878d\u5408\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u767a\u73fe\u3059\u308b\u304c\u3093\u7d30\u80deHCT116\u306e\u7d30\u80de\u682a\u306e\u6a39\u7acb\u30002019\u5e74\u5ea6\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u95a2\u6771\u652f\u90e8\u4f8b\u4f1a<\/p>\n

(3) \u6876\u7530\u51db\u3089\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u7d30\u83cc Flexivirga<\/i> alba<\/i> ST13T<\/sup>\u682a\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u907a\u4f1d\u5b50\u306e\u63a2\u7d22\u3000\u7b2c71\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(4) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u304c\u3093\u5e79\u7d30\u80de\u30e2\u30c7\u30ebmiPS-LLCcm\u306e\u7d30\u80de\u5f62\u614b\u306e\u6df1\u5c64\u5b66\u7fd2\u6cd5\u306b\u3088\u308b\u89e3\u6790\u3000\u7b2c71\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(5) \u6e21\u9089\u82f1\u660e\u3089\u3000ROS\u767a\u751f\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308bshRNA\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u304a\u3088\u3073\u89e3\u6790\u3000\u7b2c42\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(6) \u6e05\u539f\u52c7\u8f1d\u3089\u3000\u6297\u708e\u75c7\u5264\u30bb\u30ec\u30b3\u30ad\u30b7\u30d6\u306b\u3088\u308b\u30d2\u30c8\u7d50\u8178\u304c\u3093\u7d30\u80de\u6b7b\u30b7\u30b0\u30ca\u30eb\u306e\u89e3\u6790\u3000\u7b2c42\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2018\u5e74<\/em><\/p>\n

(1) \u6876\u7530\u51dc\u3089\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u7d30\u83ccFlexivirga alba<\/em> ST13\u682a\u306e\u30d5\u30e9\u30b0\u30e1\u30f3\u30c8\u89e3\u6790\u3092\u5229\u7528\u3057\u305f\u8ffd\u8de1\u6cd5\u3000\u7b2c70\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(2) Sakae Nishisako, Saori Aida, Hiroyuki Kameda, Tomonari Kasai, Atsushi Sato and Tomoyasu Sugiyama \u3000Deep-learning of cancer stem cell morphology for anti-cancer stem cell molecule screening. CBI annual meeting (2018)P5-05<\/p>\n

(3) \u6e05\u539f\u52c7\u8f1d\u3089\u3000\u86cd\u5149\u8a66\u85acJC-1\u306b\u3088\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u8a55\u4fa1\u7cfb\u3092\u5fdc\u7528\u3057\u305f\u65b0\u898fshRNA\u306e\u63a2\u7d22 \u3000\u7b2c41\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2017\u5e74<\/em><\/p>\n

(1) \u5e83\u702c\u4f51\u7d00\u3089\u3000\u5ec3\u7cd6\u871c\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3068\u305d\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u6027\u306b\u95a2\u3059\u308b\u89e3\u6790 \u7b2c69\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(2) \u4e59\u9ad8\u4fca\u5fb3\u3089\u3000TMEM117\u304c\u95a2\u4e0e\u3059\u308b\u5c0f\u80de\u4f53\u7531\u6765\u306eROS\u306e\u89e3\u660e\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(3) \u7389\u6728\u667a\u4e5f\u3089\u3000\u5c0f\u80de\u4f53\u30b9\u30c8\u30ec\u30b9\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u306b\u95a2\u4e0e\u3059\u308bTMEM117\u306e\u6a5f\u80fd\u306e\u89e3\u6790\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(4) \u5965\u5c71\u4eae\u4e4b\u3089\u3000\u30a8\u30d4\u30be\u30fc\u30de\u30eb\u8907\u88fd\u578b\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(5) \u68ee\u5ddd\u5927\u751f\u3089\u3000\u30de\u30a6\u30b9\u304c\u3093\u5e79\u7d30\u80de\u682amiPS-LLCcm\u3078\u306e\u30a8\u30d4\u30be\u30fc\u30de\u30eb\u30d9\u30af\u30bf\u30fc\u306e\u5c0e\u5165\u52b9\u7387\u306e\u691c\u8a0e\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7) \u5e73\u585a\u9054\u4e5f\u3089\u3000\u819c\u9178\u5316\u7d30\u80de\u8a55\u4fa1\u7cfb\u3092\u7528\u3044\u305f\u30ac\u30f3\u7d30\u80de\u306eROS\u767a\u751f\u306b\u95a2\u4e0e\u3059\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(8) \u7027\u653f\u5b8f\u3089\u3000SA-\u03b2-gal\u3092\u6307\u6a19\u3068\u3057\u305f\u7d30\u80de\u8001\u5316\u8a55\u4fa1\u7cfb\u306b\u3088\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c40\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2016\u5e74<\/em><\/p>\n

(1)\u3000\u6749\u5c71\u53cb\u5eb7\u3089\u3000\u4eba\u5de5\u914d\u5217\u3092\u542b\u3080shRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u652f\u63f4\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c2\u56de<\/p>\n

(2)\u3000\u7027\u653f\u5b8f\u3089\u3000\u30d2\u30c8\u7d50\u8178\u764c\u7d30\u80de\u682aHCT116 \u306b\u7d30\u80de\u8001\u5316\u3092\u8a98\u5c0e\u3059\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c2\u56de<\/p>\n

(3)\u3000\u4e59\u9ad8\u4fca\u5fb3\u3089\u3000\u30d2\u30c8\u764c\u7d30\u80de\u682a\u306e\u7d30\u80de\u6b7b\u3092\u8a98\u5c0e\u3059\u308bsiRNA\u3092\u7528\u3044\u305fROS\u767a\u751f\u306e\u89e3\u6790\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c2\u56de<\/p>\n

(4)\u3000\u5965\u5c71\u4eae\u4e4b\u3089\u3000\u30a8\u30d4\u30be\u30fc\u30de\u30eb\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305fRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u6cd5\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c2\u56de<\/p>\n

(5)\u3000\u4f0f\u898b\u7fd4\u592a\u3089\u3000\u764c\u7d30\u80deHCT116 \u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u8a55\u4fa1\u7cfb\u3092\u7528\u3044\u305fRNAi\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c2\u56de<\/p>\n

(6)\u3000\u4e59\u9ad8\u4fca\u5fb3\u3089\u3000\u30d2\u30c8\u5927\u8178\u764c\u7d30\u80de\u682aHCT116\u306e\u7d30\u80de\u6b7b\u3092\u8a98\u5c0e\u3059\u308bsiRNA\u3092\u7528\u3044\u305fROS\u767a\u751f\u306e\u89e3\u6790\u3000\u7b2c39\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7)\u3000\u6749\u5c71\u53cb\u5eb7\u3089\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u3092\u7528\u3044\u305f\u6297\u9178\u5316\u7269\u8cea\u8a55\u4fa1\u7cfb\u306e\u958b\u767a\u3000\u7b2c39\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2015\u5e74<\/em><\/p>\n

(1)\u3000\u91d1\u4e45\u4fdd\u667a\u58eb\u3089\u3000\u30bb\u30e1\u30f3\u30c8\u6539\u826f\u571f\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u6eb6\u51fa\u6db2\u306b\u304a\u3051\u308b\u653e\u7dda\u83cc Flexivirga alba<\/em> ST13T<\/sup> \u306e\u751f\u80b2\u3068\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u3000\u7b2c67\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(2)\u3000\u6c60\u4e0a\u5065\u4e8c\u3089\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u7d30\u83ccFlexivirga alba<\/em>ST13 \u682a\u306eRISA\u6cd5\u306b\u3088\u308b\u8ffd\u8de1\u3000\u7b2c67\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(3)\u3000\u6749\u5c71\u53cb\u5eb7\u3000\u30bb\u30e1\u30f3\u30c8\u306b\u542b\u307e\u308c\u308b\u516d\u4fa1\u30af\u30ed\u30e0\u306b\u3088\u308b\u6c5a\u67d3\u3068\u305d\u306e\u9664\u53bb\u5bfe\u7b56\u3000\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u57fc\u7389\u770c\u4e0d\u52d5\u7523\u9451\u5b9a\u58eb\u5354\u4f1a\u4e3b\u50ac\u3000\u571f\u58cc\u6c5a\u67d3\u5bfe\u7b56\u306e\u73fe\u72b6\u3068\u4e0d\u52d5\u7523\u8a55\u4fa1\uff08\u4e00\u822c\u516c\u958b\u8b1b\u6f14\u4f1a\uff09<\/p>\n

(4)\u3000\u4e2d\u8fbc\u7be4\u5fd7\u3089\u3000CFSE\u3092\u6307\u6a19\u3068\u3057\u3066\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3057\u305f\u30ac\u30f3\u7d30\u80de\u306e\u5206\u88c2\u3092\u6291\u5236\u3055\u305b\u308b\u65b0\u898fshRNA\u3000\u7b2c38\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(5)\u3000\u6c96\u4e2d\u671b\u3089\u3000\u30a8\u30d4\u30bd\u30fc\u30de\u30eb\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305fshRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3000\u7b2c38\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2014\u5e74<\/em><\/p>\n

(1)\u3000\u91d1\u4e45\u4fdd\u667a\u58eb\u3089\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u80fd\u3092\u3082\u3064\u653e\u7dda\u83ccFlexivirga alba<\/em> ST13T<\/sup>\u306b\u3088\u308b\u30bb\u30e1\u30f3\u30c8\u6539\u826f\u571f\u7531\u6765\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u3000\u7b2c66\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(2)\u3000\u6c60\u4e0a\u5065\u4e8c\u3089\u3000\u5ec3\u7cd6\u871c\u306b\u3088\u308b\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u306e\u96fb\u6c17\u5316\u5b66\u7684\u8a55\u4fa1\u3000\u7b2c66\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(3)\u3000\u5e2b\u5ca1\u4fca\u592a\u6717\u3089\u3000\u6d3b\u6027\u9178\u7d20\u7a2e\u30ec\u30d9\u30eb\u3068\u6297\u30ac\u30f3\u5264\u306e\u7d30\u80de\u5897\u6b96\u6291\u5236\u52b9\u679c\u3078\u306e\u5f71\u97ff\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(4)\u3000Alamri Fatemah\u3089\u3000shRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u3088\u308a\u5f97\u3089\u308c\u305fshRNA\u306b\u3088\u308b\u521d\u671f\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u8a98\u5c0e\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(5)\u3000\u4e2d\u6751\u76f4\u8f1d\u3089\u3000\u7d50\u8178\u764c\u7d30\u80de\u682aHCT116\u306b\u7d30\u80de\u8001\u5316\u3092\u8a98\u5c0e\u3059\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(6)\u3000\u5927\u585a\u5eb7\u4ecb\u3089\u3000\u30ac\u30f3\u7d30\u80de\u682aHCT116\u3067ROS\u3092\u767a\u751f\u3055\u305b\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7)\u3000\u4f50\u85e4\u7422\u3089\u3000\u819c\u9178\u5316\u8a55\u4fa1\u7cfb\u3092\u7528\u3044\u305f\u30ac\u30f3\u7d30\u80de\u306e\u6d3b\u6027\u9178\u7d20\u767a\u751f\u306b\u95a2\u4e0e\u3059\u308bshRNA\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0 \u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(8)\u3000\u4e2d\u8fbc\u7be4\u5fd7\u3089\u3000\u30d2\u30c8\u7d50\u8178\u30ac\u30f3\u7d30\u80de\u682aHCT1116\u306e\u5206\u88c2\u3092\u6291\u5236\u3055\u305b\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(9)\u3000\u4f50\u85e4\u7559\u5b9f\u3089\u3000\u96e3\u6eb6\u6027\u86cd\u5149\u8a66\u85acC11BODIPY581\/591\u3092\u7528\u3044\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\uff08Schmidtea mediterranea<\/em>\uff09\u306e\u6d3b\u6027\u9178\u7d20\u306e\u89e3\u6790 \u7b2c37\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2013\u5e74<\/em><\/p>\n

(1)\u3000\u9ad8\u6728 \u60a0\u4ecb\u3089\u3001\u3000CoQ9\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50Smed-dlp1\u767a\u73fe\u6291\u5236\u3057\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u306b\u304a\u3051\u308bCoQ9\u7d66\u990c\u52b9\u679c\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(2)\u3000\u6e21\u90e8\u5b97\u5e78\u3089\u3001\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u7d44\u7e54\u306e\u5e79\u7d30\u80de\u3068\u6d3b\u6027\u9178\u7d20\u7a2e\u306e\u4e8c\u91cd\u6a19\u8b58\u6cd5\u306e\u958b\u767a\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(3)\u3000\u4e2d\u4e0b\u664b\u4e00\u90ce\u3089\u3001\u3000\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u6d88\u5931\u3092\u6307\u6a19\u3068\u3057\u305fHCT116\u306e\u65b0\u898fshRNA\u63a2\u7d22\u3000 \u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(4)\u3000\u7389\u6728\u667a\u4e5f\u3089\u3001\u3000\u764c\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u306b\u5f71\u97ff\u3059\u308bshRNA\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(5)\u3000\u4f50\u85e4\u7422\u3089\u3001\u3000\u819c\u9178\u5316\u8a55\u4fa1\u7cfb\u3092\u7528\u3044\u305f\u30ac\u30f3\u7d30\u80de\u306e\u6d3b\u6027\u9178\u7d20\u767a\u751f\u306b\u95a2\u4e0e\u3059\u308bshRNA\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(6)\u3000\u5927\u585a\u5eb7\u4ecb\u3089\u3001\u3000ROS\u86cd\u5149\u6307\u793a\u85accarboxy-H2<\/sub>DCFDA,AM\u3092\u7528\u3044\u305f\u3001\u30ac\u30f3\u7d30\u80de\u682aHCT116\u306b\u304a\u3051\u308b\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7)\u3000\u9ad8\u6a4b\u5f37\u5fd7\u3089\u3001\u3000\u751f\u7d30\u80de\u304a\u3088\u3073\u6b7b\u7d30\u80de\u86cd\u5149\u67d3\u8272\u3092\u6307\u6a19\u3068\u3057\u305f\u8a55\u4fa1\u7cfb\u3092\u7528\u3044\u305f\u65b0\u898fshRNA\u306e\u63a2\u7d22\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(8)\u3000\u938c\u585a\u5065\u592a\u3089\u3001\u3000siRNA\u306e\u6a5f\u80fd\u4e88\u6e2c\u306e\u305f\u3081\u306e\u89e3\u6790\u652f\u63f4\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9\u3000\u7b2c36\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2012\u5e74<\/em><\/p>\n

(1)\u3000\u7530\u7551\u5065\u591a\u3089\u3001\u3000Smed-dlp1(RNAi)<\/em>\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u5f62\u614b\u7570\u5e38\u306b\u5bfe\u3059\u308b\u6297\u9178\u5316\u7269\u8cea\u306e\u5f71\u97ff\u3000\u7b2c9\u56de\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5354\u4f1a\u7814\u7a76\u4f1a<\/p>\n

(2)\u3000\u6749\u5c71\u53cb\u5eb7\u3089\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u3092\u9084\u5143\u3059\u308b\u653e\u7dda\u83ccF. alba<\/em> ST13T<\/sup>\u682a\u306eTEM\u89e3\u6790\u3000\u7b2c64\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(3)\u3000\u571f\u91ce\u7fd4\u592a\u3089\u3001\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u907a\u4f1d\u5b50\u89e3\u6790\u306e\u305f\u3081\u306eshRNA\u3092\u7528\u3044\u305f\u65b0\u898fRNAi\u6cd5 \u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(4)\u3000\u52a0\u3005\u898b\u4eae\u3089\u3001\u3000\u764c\u7d30\u80de\u306e\u6d3b\u6027\u9178\u7d20\u767a\u751f\u306b\u5f71\u97ff\u3059\u308bshRNA\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0 \u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(5)\u3000\u6cb3\u6751\u5d07\u96c4\u3089\u3001\u3000\u5927\u898f\u6a21\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u30c7\u30fc\u30bf\u89e3\u6790\u306b\u3088\u308b\u6709\u610f\u306a\u767a\u73fe\u91cf\u5909\u5316\u3092\u793a\u3059\u907a\u4f1d\u5b50\u306e\u691c\u51fa \u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(6)\u3000\u938c\u585a\u5065\u592a\u3089\u3001\u3000siRNA\u306e\u6a5f\u80fd\u4e88\u6e2c\u306e\u305f\u3081\u306e\u89e3\u6790\u652f\u63f4\u30b7\u30b9\u30c6\u30e0\u306e\u69cb\u7bc9 \u3000\u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7)\u3000\u5f35\u66ff\u771e\u543e\u3089\u3001\u3000BODIPY 581\/591 C11\u3092\u7528\u3044\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u51cd\u7d50\u7d44\u7e54\u5207\u7247\u306e\u6d3b\u6027\u9178\u7d20\u7a2e(ROS)\u306e\u89e3\u6790\u6cd5 \u7b2c35\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2011\u5e74<\/em><\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3000\u30af\u30ed\u30e0\u9664\u53bb\u30b7\u30b9\u30c6\u30e0\u306b\u6709\u7528\u306a\u5fae\u751f\u7269\u3000\u30e1\u30bf\u30eb\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u7814\u7a76\u4f1a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<\/p>\n

(2) Bay Daniyah\u3089\u3001\u3000CoQ\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50Smed-coq2<\/em>\u3092RNAi\u6cd5\u3067\u963b\u5bb3\u3057\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u89e3\u6790\u3000\u7b2c8\u56de\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5354\u4f1a\u7814\u7a76\u4f1a<\/p>\n

(3) \u6749\u5c71\u53cb\u5eb7\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u65b0\u9673\u4ee3\u8b1d\u3068\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u306b\u95a2\u3059\u308b\u767a\u8868\u30005th SFRR-Asia, 8th ASMRM, 11th J-mit\u5408\u540c\u56fd\u969b\u4f1a\u8b70\uff08\u9e7f\u5150\u5cf6\uff09<\/p>\n

(4) \u6749\u5c71\u53cb\u5eb7\u3089\u3001\u3000\u65b0\u898f\u653e\u7dda\u83ccST13\u682a\u3067\u51e6\u7406\u3057\u305f\u30af\u30ed\u30e0\u542b\u6709\u6c88\u6bbf\u7269\u306eXANES\u89e3\u6790\u3000\u7b2c63\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(5) \u6749\u5c71\u53cb\u5eb7\u3000ShRNA\u30e9\u30a4\u30d6\u30ea\u30fc\u4f5c\u88fd\u6cd5\u306b\u95a2\u3059\u308b\u767a\u8868\u3000BIT’s 1st WCSR-2011(Shenzhen, China)<\/p>\n

(6) \u897f\u5ddd\u96c4\u4e8c\u3089\u3001\u3000PCR\u3092\u4f7f\u308f\u306a\u3044\u65b0\u898f\u306ashRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u4f5c\u88fd\u6cd5\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(7) \u52a0\u85e4\u96c4\u98db\u3089\u3001\u3000\u764c\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u96fb\u4f4d\u306b\u5f71\u97ff\u3059\u308bshRNA\u63a2\u7d22\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(8) \u5c71\u4e0b\u77ac\u3089\u3001\u3000\u764c\u7d30\u80de\u306e\u6d3b\u6027\u9178\u7d20\u767a\u751f\u306b\u5f71\u97ff\u3059\u308bshRNA\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(9) \u7530\u7551\u5065\u591a\u3089\u3001\u3000CoQ\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50Smed-dlp1<\/em>\u767a\u73fe\u6291\u5236\u3057\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u306b\u304a\u3051\u308bCoQ\u88dc\u7d66\u52b9\u679c\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(10) \u7530\u4e2d\u51b4\u5b50\u3089\u3001\u3000Smed-dlp1(RNAi)<\/em>\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u65b0\u9673\u4ee3\u8b1d\u306b\u5bfe\u3059\u308b\u6297\u9178\u5316\u7269\u8cea\u7d66\u990c\u52b9\u679c\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

(11) \u9234\u6728\u6625\u9999\u3089\u3001\u3000\u86cd\u5149\u8272\u7d20H2<\/sub>DCFDA\u3092\u7528\u3044\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u7d30\u80de\u5185\u6d3b\u6027\u9178\u7d20\u6e2c\u5b9a\u6cd5\u3000\u7b2c34\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a<\/p>\n

2010\u5e74<\/em><\/p>\n

(1) \u539f\u7530\u5343\u660e\u3089\u3001\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308bCoQ\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50\u306e\u5f79\u5272\u89e3\u6790\u3000\u7b2c7\u56de\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5354\u4f1a\u7814\u7a76\u4f1a<\/p>\n

(2) \u6749\u5c71\u53cb\u5eb7\u3089\u3001\u3000\u65b0\u898f\u653e\u7dda\u83ccST13\u682a\u306b\u3088\u308b\u516d\u4fa1\u30af\u30ed\u30e0\u9664\u53bb\u306b\u6709\u52b9\u306a\u57f9\u5730\u306e\u691c\u8a0e\u3000\u7b2c62\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(3) \u5869\u7530\u6bc5\u3089\u3001\u3000Smed-dlp1 (RNAi)<\/em>\u30d7\u30e9\u30ca\u30ea\u30a2\u3078\u306e\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u7d66\u990c\u52b9\u679c\u3000BMB2010<\/p>\n

(4) \u7530\u4e2d\u5553\u4e00\u3089\u3001\u3000\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50coq4<\/em> RNAi\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u8868\u73fe\u578b\u89e3\u6790\u3000BMB2010<\/p>\n

2009\u5e74<\/em><\/p>\n

(1) \u5869\u539f\u7531\u5b9f\u5b50\u3089\u3001\u3000COQ1 dsRNA\u6295\u4e0e\u6cd5\u306e\u9055\u3044\u306b\u3088\u308b\u30d7\u30e9\u30ca\u30ea\u30a2\u3078\u306eRNAi\u52b9\u679c\u306e\u691c\u8a0e\u3000\u7b2c61\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(2) \u5869\u7530\u6bc5\u3089\u3001\u3000\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50DLP1<\/em>\u306e\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308bRNAi\u3092\u7528\u3044\u305f\u5f79\u5272\u89e3\u6790\u3000\u7b2c61\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(3)\u95a2\u6c5f\u8056\u8f1d\u3089\u3001\u3000\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5408\u6210\u9175\u7d20\u907a\u4f1d\u5b50COQ5<\/em>\u306e\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308bRNAi\u3092\u7528\u3044\u305f\u5f79\u5272\u89e3\u6790\u3000\u7b2c61\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(4) \u53e4\u7530\u4e98\u3089\u3001\u3000\u65b0\u898f\u30e9\u30f3\u30e9\u30e0siRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u4f5c\u88fd\u6cd5\u3067\u4f5c\u88fd\u3057\u305fshRNA\u306b\u3088\u308bRNAi\u52b9\u679c\u306e\u691c\u8a0e\u3000\u7b2c61\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

(5) \u6749\u6238\u6d69\u7d00\u3089\u3001\u3000\u65b0\u898f\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u7d30\u83ccST13\u682a\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u89e3\u6790\u3000\u7b2c61\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a<\/p>\n

2008\u5e74<\/em><\/p>\n

(1) \u539f\u7530\u5343\u660e\u3089\u3001\u3000\u30bd\u30ce\u30dd\u30ec\u30fc\u30b7\u30e7\u30f3\u6cd5\u3092\u7528\u3044\u305f\u30d7\u30e9\u30ca\u30ea\u30a2\u3078\u306e\u9ad8\u5206\u5b50\u5c0e\u5165\u6cd5\u3000\u7b2c60\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(2) \u5869\u539f\u7531\u5b9f\u5b50\u3089\u3001\u3000\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0\uff31\u5408\u6210\u9175\u7d20COQ1<\/em>\u306e\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308bRNAi\u3092\u7528\u3044\u305f\u5f79\u5272\u89e3\u6790\u3000\u7b2c60\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(3) \u897f\u5ddd\u96c4\u4e8c\u3089\u3001\u3000\u30e9\u30f3\u30c0\u30e0siRNA\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u306e\u65b0\u898f\u4f5c\u88fd\u6cd5\u3000\u7b2c60\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(4) \u6749\u6238\u6d69\u7d00\u3089\u3001\u3000\u65b0\u898f\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u83cc\u306b\u304a\u3051\u308b\u6027\u72b6\u89e3\u6790\u3000\u7b2c60\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(5) \u6749\u5c71\u53cb\u5eb7\u3089\u3001\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308b\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u306e\u5f79\u5272\u3000\u7b2c5\u56de\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u5354\u4f1a\u7814\u7a76\u4f1a<\/p>\n

(6) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u6c5a\u67d3\u6d44\u5316\u5fae\u751f\u7269\u3068\u5229\u7528\u3059\u308b\u305f\u3081\u306e\u8ab2\u984c\u3000TAMA-TLO\u6280\u8853\u8b1b\u6f14\u4f1a<\/p>\n

(7) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u5fae\u751f\u7269\u306b\u3088\u308b\u516d\u4fa1\u30af\u30ed\u30e0\u6c5a\u67d3\u306e\u6d44\u5316\u3000\u7570\u696d\u7a2e\u4ea4\u6d41\u30bb\u30df\u30ca\u30fc<\/p>\n

(8) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u30d7\u30e9\u30ca\u30ea\u30a2\u518d\u751f\u306b\u304a\u3051\u308b\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q\u306e\u5f79\u5272\u3000\u300c\u5065\u5eb7\u5bff\u547d\u5ef6\u9577\u306e\u305f\u3081\u306e\u65b0\u6297\u9178\u5316\u6226\u7565\u300d\u516c\u958b\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<\/p>\n

2007\u5e74<\/em><\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u3092\u9084\u5143\u3059\u308b\u65b0\u898f\u5fae\u751f\u7269\u306b\u3088\u308b\u74b0\u5883\u6d44\u5316\u3000\u7b2c59\u56de\u65e5\u672c\u751f\u7269\u5de5\u5b66\u4f1a\u5927\u4f1a<\/p>\n

(2) \u6749\u5c71\u53cb\u5eb7\u3089\u3001\u3000Snf5\u306eRNAi\u306f\u30d7\u30e9\u30ca\u30ea\u30a2\u306e\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u518d\u751f\u306b\u5f71\u97ff\u3059\u308b\u3000BMB2007<\/p>\n

(3) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u3092\u9084\u5143\u3059\u308b\u65b0\u898f\u5fae\u751f\u7269\u306b\u3088\u308b\u74b0\u5883\u6d44\u5316\u3000\u56fd\u969b\u30d0\u30a4\u30aaEXPO 2007<\/p>\n

(4) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u3092\u9084\u5143\u3059\u308b\u65b0\u898f\u5fae\u751f\u7269\u306b\u3088\u308b\u74b0\u5883\u6d44\u5316\u3000\u7b2c8\u56de\u30d3\u30b8\u30cd\u30b9\u30d5\u30a7\u30a2 from TAMA<\/p>\n

2003\u5e74<\/em><\/p>\n

(1) \u6e21\u8fba\u548c\u5f66\u3089\u3001\u3000\u53d7\u5bb9\u4f53\u3068\u30ea\u30ac\u30f3\u30c9\u907a\u4f1d\u5b50\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u914d\u5217\u89e3\u6790\u3000\u7b2c26\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a<\/p>\n

Publications<\/strong><\/p>\n

Anti-cancer pharmacology<\/em><\/span><\/p>\n

(1) Maruyama, R., Kiyohara, Y., Kudo, Y. and Sugiyama, T., <\/strong>2023. Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancer<\/a>. Naunyn Schmiedebergs Arch. Pharmacol. 396:1171-1185<\/p>\n

(2) Maruyama, R. and T. Sugiyama<\/strong>, 2023. ER Stress Decreases Gene Expression Of Transmembrane Protein 117 Via Activation of PKR-like ER Kinase<\/a>. Cell Biochemistry and Biophysics, 81: 459-468<\/p>\n

(3) Long, H., Sugiyama, T<\/strong>. and Muramatsu, H., 2025. Difference in cell death response between mitomycin C and 5\u2011fluorouracil treatment studied using quartz crystal microbalance combined with simultaneous monitoring of viable cells.<\/span> Journal of Biological Physics, 52:article no 2<\/p>\n

RNAi technology<\/u><\/em><\/p>\n

(1) Nishikawa, Y. and Sugiyama, T.,<\/strong> 2010. A shRNA library constructed through the generation of loop-stem-loop DNA<\/a>. J Gene Medicine. 12:927-933<\/p>\n

(2) Shiobara, Y., C. Harada, T. Shiota, K. Sakamoto, K. Kita, S. Tanaka, K. Tabata, K. Sekie, Y. Yamamoto and T. Sugiyama<\/strong>., 2015. Knockdown of the coenzyme Q synthesis gene Smed-dlp1<\/em> affects planarian regeneration and tissue homeostasis<\/a>. Redox Biology. 6:599-606<\/p>\n

(3) Kamatuka, K., M. Hattori, and T. Sugiyama<\/strong>., 2016. shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library<\/a>. EURASIP Journal on Bioinformatics & Systems Biology (1):7. 1-9<\/p>\n

(4) Tamaki, T., K. Kamatuka, T. Sato, S. Morooka, K. Otsuka, H. Hattori and T. Sugiyama<\/strong>., 2017. A novel transmembrane protein defines the endoplasmic reticulum stress-induced cell death pathway<\/a>. Biochemical and Biophysical Research Communications. 486:149-155<\/p>\n

(5) R. Maruyama, Y. Kudo, T. Sugiyama.<\/strong>, 2023. A new strategy for screening novel functional genes involved in reduction of lipid droplet accumulation<\/a>. BioFactors. on line first published on 20 Nov.<\/p>\n

Metal biotechnology<\/em><\/span><\/p>\n

(1) Anzai, K., Sugiyama,<\/strong> T.<\/strong>, Sukisaki, M., Sakiyama, Y., Otoguro, M. and Ando, K., 2011. Flexivirga alba<\/em> gen. nov., sp. nov., an actinobacterial taxon in the family Dermacoccaceae<\/em><\/a>. J Antibiot. 64:613-616<\/p>\n

(2) Sugiyama, T.<\/strong>, Sugito H., Mamiya K., Suzuki Y., Ando K. and Ohnuki T., 2012.\u00a0 Hexavalent chromium reduction by an actinobacterium Flexivirga alba<\/em> ST13T<\/sup> in the family Dermacoccaceae<\/em><\/a>. J Biosci Bioeng. 113:367-371<\/p>\n

(3) Sugiyama, T.<\/strong>, Sakaguchi T., 2014. Electron microscopy and X-ray analysis of Cr-containing precipitates synthesized by newly isolated actinobacterium, Flexivirga alba<\/em> ST13T<\/sup><\/a>. Indian J. Microbiology. 54:358-360<\/p>\n

(4) Ikegami, K., Hirose Y., Sakashita H., Maruyama R. and Sugiyama, T.,<\/strong> 2020. Role of polyphenol in sugarcane molasses as a nutrient for hexavalent chromium bioremediation using bacteria<\/a>, Chemosphere. 250:126267<\/p>\n

Artificial intelligence technology<\/span><\/em><\/p>\n

(1) Aida, S., Kameda, H., Nishisako, S., Kasai, T., Sato, A., Sugiyama, T.<\/strong>, 2020. Conditional Generative Adversarial Networks to Model iPSC-Derived Cancer Stem Cells<\/a>. Journal of Advanced Computational Intelligence and Intelligent Informatics 24, 134-141.<\/p>\n

(2) Aida, S., Okugawa, J., Fujisaka, S., Kasai, T., Kameda, H., Sugiyama, T.<\/strong>, 2020. Deep Learning of Cancer Stem Cell Morphology Using Conditional Generative Adversarial Networks<\/a>. Biomolecules 10:931<\/p>\n

(3) Hanai, Y., Ishihata, H., Zhang, Z., Maruyama, R., Kasai, T., Kameda, H., Sugiyama, T.<\/strong>, 2022. Temporal and locational values of images affecting the deep learning of cancer stem cell morphology<\/a>. Biomedicines 10(5):941<\/p>\n

(4) Zhang, Z, Ishihata, H, Maruyama, R, Kasai, T, Kameda, H, Sugiyama, T<\/strong> (2023) Deep Learning of Phase-Contrast Images of Cancer Stem Cells Using a Selected Dataset of High Accuracy Value Using Conditional Generative Adversarial Networks<\/a>. International Journal of Molecular Sciences 24(6):5323<\/p>\n

(5) M. Fujisawa, T. Ohara, Y. Shimada, K. Takeuchi, T. Shimayoshi, T. Sugiyama<\/strong>, T. Higuchi, Y. Iwasaki, A. Matsukawa, (2026). Direct Measurement and AI-based Inference Reveal Histological Section Thickness as a Variable Physical Property Accessible from Routine H&E Images., Laboratory Investigation, Article: <\/span>106166<\/p>\n

Human cDNA project in Japan<\/u><\/em><\/p>\n

(1) Nishikawa, T., K. Murakami, N. Harada, T. Ota, T. Sugiyama<\/strong>, K. Nagai, R. Irie, H. Matui, M. Suwa, and T. Isogai., (2000). An integrated analysis and database system for full-length cDNA. Genome Inform Ser Workshop Genome Inform. 11:12-23.<\/p>\n

(2) Harada, N., K. Murakami, T. Nishikawa, T. Sugiyama<\/strong>, T. Ota, R. Irie, K. Nagai and T. Isogai (2000). “A Database System for cDNA Expression Profile Using ESTs of Oligo-Capping Clones and UniGene.” Genome Informatics 11: 370-371.<\/p>\n

(3) Sugiyama, T.<\/strong>, S. Ishii, K. Saito, J. Yamamoto, T. Isogai, and T. Ota., 2000. Preparation of sensitive and specific oligonucleotide probes tailed using terminal transferase and dITP<\/a>. Biotechniques. 28:486-90.<\/p>\n

(4) Yudate, H.T., M. Suwa, R. Irie, H. Matsui, T. Nishikawa, Y. Nakamura, D. Yamaguchi, Z.Z. Peng, T. Yamamoto, K. Nagai, K. Hayashi, T. Otsuki, T. Sugiyama<\/strong>, T. Ota, Y. Suzuki, S. Sugano, T. Isogai, and Y. Masuho., 2001. HUNT: launch of a full-length cDNA database from the Helix Research Institute<\/a>. Nucleic Acids Res. 29:185-8.<\/p>\n

(5) Sugiyama, T.<\/strong>, S. Ishii, J. Yamamoto, R. Irie, K. Saito, T. Otuki, A. Wakamatsu, Y. Suzuki, Y. Hio, T. Ota, T. Nishikawa, S. Sugano, Y. Masuho, and T. Isogai., 2002. cDNA macroarray analysis of gene expression in synoviocytes stimulated with TNFalpha<\/a>. FEBS Lett. 517:121-8.<\/p>\n

(6)\u00a0Nishikawa, T., K. Murakami, K. Hayashi, H. Sato, T. Otsuki, N. Kasahara, T. Yasuda, K. Kimura, K. Nagai, R. Irie, T. Sugiyama<\/strong> and T. Isogai (2002). “An Extracting System of Accurate ORFs from cDNA Sequences.” Genome Informatics 13: 545-547.<\/p>\n

(7) Imabayashi, H., T. Mori, S. Gojo, T. Kiyono, T. Sugiyama<\/strong>, R. Irie, T. Isogai, J. Hata, Y. Toyama, and A. Umezawa., 2003. Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis<\/a>. Exp Cell Res. 288:35-50.<\/p>\n

(8) Ota, T., Y. Suzuki, T. Nishikawa, T. Otsuki, T. Sugiyama<\/strong>, R. Irie, A. Wakamatsu, K. Hayashi, H. Sato, K. Nagai, K. Kimura, H. Makita, M. Sekine, M. Obayashi, T. Nishi, T. Shibahara, T. Tanaka, S. Ishii, J.I. Yamamoto, K. Saito, Y. Kawai, Y. Isono, Y. Nakamura, K. Nagahari, K. Murakami, T. Yasuda, T. Iwayanagi, M. Wagatsuma, A. Shiratori, H. Sudo, T. Hosoiri, Y. Kaku, H. Kodaira, H. Kondo, M. Sugawara, M. Takahashi, K. Kanda, T. Yokoi, T. Furuya, E. Kikkawa, Y. Omura, K. Abe, K. Kamihara, N. Katsuta, K. Sato, M. Tanikawa, M. Yamazaki, K. Ninomiya, T. Ishibashi, H. Yamashita, K. Murakawa, K. Fujimori, H. Tanai, M. Kimata, M. Watanabe, S. Hiraoka, Y. Chiba, S. Ishida, Y. Ono, S. Takiguchi, S. Watanabe, M. Yosida, T. Hotuta, J. Kusano, K. Kanehori, A. Takahashi-Fujii, H. Hara, T.O. Tanase, Y. Nomura, S. Togiya, F. Komai, R. Hara, K. Takeuchi, M. Arita, N. Imose, K. Musashino, H. Yuuki, A. Oshima, N. Sasaki, S. Aotsuka, Y. Yoshikawa, H. Matsunawa, T. Ichihara, N. Shiohata, S. Sano, S. Moriya, H. Momiyama, N. Satoh, S. Takami, Y. Terashima, O. Suzuki, S. Nakagawa, A. Senoh, H. Mizoguchi, Y. Goto, F. Shimizu, H. Wakebe, H. Hishigaki, T. Watanabe, A. Sugiyama, et al., 2004. Complete sequencing and characterization of 21,243 full-length human cDNAs<\/a>. Nature Genet. 36:40-45.<\/p>\n

Smooth muscle cell<\/u><\/em><\/p>\n

(1) Damiani, E., T. Sugiyama<\/strong>, K. Shimamura, L. Greci, and Y. Matsuda. 1998. Altered expression of alpha-actin, smooth muscle myosin heavy chain-1 and calponin in cultured smooth muscle cells by oxidized low density lipoproteins<\/a>. FEBS Lett. 425:123-5.<\/p>\n

(2) Masuda, T., K. Ohmi, H. Yamaguchi, K. Hasegawa, T. Sugiyama<\/strong>, Y. Matsuda, M. Iino, and Y. Nonomura. 1999. Growing and differentiating characterization of aortic smooth muscle cell line, p53LMAC01 obtained from p53 knock out mice<\/a>. Mol Cell Biochem. 190:99-104.<\/p>\n

(3) Sugiyama, T.<\/strong>, K. Hasegawa, N. Yanai, K. Mikoshiba, M. Obinata, and Y. Matsuda. 1999. Alteration of the increase in intracellular [Ca(2+)] in proliferating smooth muscle cells<\/a>. Biochem Biophys Res Commun. 264:774-6.<\/p>\n

Inositol 1,4,5-trisphosphate receptor<\/u><\/em><\/p>\n

(1) Sugiyama, T.<\/strong>, A. Furuya, T. Monkawa, M. Yamamoto-Hino, S. Satoh, K. Ohmori, A. Miyawaki, N. Hanai, K. Mikoshiba, and M. Hasegawa. 1994. Monoclonal antibodies distinctively recognizing the subtypes of inositol 1,4,5-trisphosphate receptor: application to the studies on inflammatory cells<\/a>. FEBS Lett. 354:149-54.<\/p>\n

(2) Sugiyama, T.<\/strong>, M. Yamamoto-Hino, A. Miyawaki, T. Furuichi, K. Mikoshiba, and M. Hasegawa. 1994. Subtypes of inositol 1,4,5-trisphosphate receptor in human hematopoietic cell lines: dynamic aspects of their cell-type specific expression<\/a>. FEBS Lett. 349:191-6.<\/p>\n

(3) Yamamoto-Hino, M., T. Sugiyama<\/strong>, K. Hikichi, M.G. Mattei, K. Hasegawa, S. Sekine, K. Sakurada, A. Miyawaki, T. Furuichi, M. Hasegawa, and et al. 1994. Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors<\/a>. Receptors Channels. 2:9-22.<\/p>\n

(4) Monkawa, T., A. Miyawaki, T. Sugiyama<\/strong>, H. Yoneshima, M. Yamamoto-Hino, T. Furuichi, T. Saruta, M. Hasegawa, and K. Mikoshiba. 1995. Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits<\/a>. J Biol Chem. 270:14700-4.<\/p>\n

(5) Yamamoto-Hino, M., A. Miyawaki, H. Kawano, T. Sugiyama<\/strong>, T. Furuichi, M. Hasegawa, and K. Mikoshiba. 1995. Immunohistochemical study of inositol 1,4,5-trisphosphate receptor type 3 in rat central nervous system<\/a>. Neuroreport. 6:273-6.<\/p>\n

(6) Sugiyama, T.<\/strong>, M. Yamamoto-Hino, K. Wasano, K. Mikoshiba, and M. Hasegawa. 1996. Subtype-specific expression patterns of inositol 1,4,5-trisphosphate receptors in rat airway epithelial cells<\/a>. J Histochem Cytochem. 44:1237-42.<\/p>\n

(7) Monkawa, T., M. Hayashi, A. Miyawaki, T. Sugiyama<\/strong>, M. Yamamoto-Hino, M. Hasegawa, T. Furuichi, K. Mikoshiba, and T. Saruta. 1998. Localization of inositol 1,4,5-trisphosphate receptors in the rat kidney<\/a>. Kidney Int. 53:296-301.<\/p>\n

(8) Yamamoto-Hino, M., A. Miyawaki, A. Segawa, E. Adachi, S. Yamashina, T. Fujimoto, T. Sugiyama<\/strong>, T. Furuichi, M. Hasegawa, and K. Mikoshiba. 1998. Apical vesicles bearing inositol 1,4,5-trisphosphate receptors in the Ca2+ initiation site of ductal epithelium of submandibular gland<\/a>. J Cell Biol. 141:135-42.<\/p>\n

(9) Hamada, T., T. Niki, P. Ziging, T. Sugiyama<\/strong>, S. Watanabe, K. Mikoshiba, and N. Ishida. 1999. Differential expression patterns of inositol trisphosphate receptor types 1 and 3 in the rat suprachiasmatic nucleus<\/a>. Brain Res. 838:131-5.<\/p>\n

(10) Sugiyama, T.<\/strong>, Y. Matsuda, and K. Mikoshiba. 2000. Inositol<\/strong> 1,4,5-trisphosphate receptor associated with focal contact cytoskeletal proteins<\/a>. FEBS Lett. 466:29-34.<\/p>\n

Transgenic fish<\/u><\/em><\/p>\n

(1) Tamiya, E., T. Sugiyama<\/strong>, K. Masaki, A. Hirose, T. Okoshi, and I.Karube. 1990. Spatial imaging of luciferase gene expression in transgenic fish<\/a>. Nucleic Acids Res. 18:1072.<\/p>\n

T. Sugiyama published DNA sequences in GenBank\/DDBJ\/EMBL<\/strong><\/p>\n

human genes: 1,613,746<\/p>\n

mouse genes: 2<\/p>\n

planarian genes: 2<\/p>\n

bacterial gene: 1<\/p>\n

Books<\/strong><\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u5fae\u751f\u7269\u306b\u3088\u308b\u516d\u4fa1\u30af\u30ed\u30e0\u6c5a\u67d3\u306e\u6d44\u5316\u3000(2009) \u30e1\u30bf\u30eb\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306b\u3088\u308b\u74b0\u5883\u4fdd\u5168\u3068\u8cc7\u6e90\u56de\u53ce\u3000\u690d\u7530\u5145\u7f8e\u3000\u6c60\u9053\u5f66\u3000\u76e3\u4fee\u3001\u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248<\/p>\n

(2) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u7d44\u63db\u3048DNA\u6280\u8853\u3000\uff082005\uff09\u30d0\u30a4\u30aa\u30cb\u30af\u30b9\u5b66\u4e8b\u5178\u3000\u8efd\u90e8\u5f81\u592b\u3000\u7de8\u3001\u4e38\u5584<\/p>\n

(3) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u30d0\u30a4\u30aa\u30ec\u30e1\u30c7\u30a3\u30a8\u30fc\u30b7\u30e7\u30f3\u3000\uff082012\uff09\u56f3\u89e3\u74b0\u5883\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u5165\u9580\u3000\u8efd\u90e8\u5f81\u592b\u3000\u7de8\u8457\u3001\u65e5\u520a\u5de5\u696d\u65b0\u805e\u793e<\/p>\n

(4) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u74b0\u5883\u6c5a\u67d3\u91cd\u91d1\u5c5e\u3000\u30af\u30ed\u30e0\u3000\uff082014\uff09 \u5fae\u751f\u7269\u3068\u91d1\u5c5e\u8cc7\u6e90\u306e\u306f\u306a\u3057\u3000\u5730\u7403\u3092\u6551\u3046\u30e1\u30bf\u30eb\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3000\u5c71\u4e0b\u5149\u96c4\u30fb\u6e05\u548c\u6210\u3000\u7de8\u8457\u3001\u6210\u5c71\u5802\u66f8\u5e97<\/p>\n

(5) Hiroyuki Kameda, Hiroaki Ishihata & Tomoyasu Sugiyama, Deep Learning of Cancer Stem Cell Morphology, (2024) Methods in Molelular Biology, Editors: Federica Papaccio, Gianpaolo Papaccio, Springer nature publisher<\/p>\n

\u5c02\u9580\u60c5\u5831\u8a8c<\/strong><\/p>\n

(1) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u304c\u3093\u5e79\u7d30\u80de\u306e\u5f62\u614b\u3092\u8b58\u5225\u3059\u308b\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\uff082020\uff09\u6708\u520aBIOINDUSTRY \u7b2c37\u5dfb12\u53f757-64\u9805\u3001\u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248<\/p>\n

(2) \u4e38\u5c71\u7adc\u4eba\u3001\u6749\u5c71\u53cb\u5eb7\u3001\u3000\u75db\u307f\u6b62\u3081\u533b\u85ac\u54c1\u300c\u30bb\u30ec\u30b3\u30ad\u30b7\u30d6\u300d\u306e\u65b0\u305f\u306a\u6297\u304c\u3093\u4f5c\u7528\u6a5f\u69cb\u3092\u767a\u898b\u301c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u4ecb\u3057\u305f\u304c\u3093\u7d30\u80de\u6b7b\u8a98\u5c0e\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u691c\u8a3c\u301c\uff082023\uff09\u6708\u520aBIOINDUSTRY \u7b2c40\u5dfb4\u53f751-56\u9805\u3001\u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248<\/p>\n

(3) \u6749\u5c71\u53cb\u5eb7\u3001\u3000\u4f4d\u76f8\u5dee\u9855\u5fae\u93e1\u753b\u50cf\u3092\u7528\u3044\u3066\u304c\u3093\u5e79\u7d30\u80de\u3092\u9ad8\u7cbe\u5ea6\u306b\u8b58\u5225\u3059\u308b\u751f\u6210\u7cfb\u4eba\u5de5\u77e5\u80fd\u306e\u958b\u767a\uff082023\uff09\u6708\u520aBIOINDUSTRY \u7b2c40\u5dfb9\u53f791-95\u9805\u3001\u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248<\/p>\n

\u7279\u8a31<\/strong><\/p>\n

(1)\u3000\u6749\u5c71\u3000\u5927\u7530\u3000\u77f3\u4e95\u3000\u82e5\u677e\u3001\u3000\u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\u30d7\u30ed\u30fc\u30d6\u3000\u7279\u98582000-582552
\n(2)\u3000\u5927\u7530\u3000\u897f\u5ddd\u3000\u6cb3\u5408\u3000\u78ef\u8c9d\u3000\u677e\u672c\u3000\u6749\u5c71\u3001\u3000\u8840\u7ba1\u65b0\u751f\u306b\u95a2\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u304a\u3088\u3073\u8a72\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3001\u3000\u7279\u9858\u5e7311-99901
\n(3)\u3000\u8a2d\u697d\u3000\u4f50\u85e4\u3000\u698a\u539f\u3000\u53e4\u8c37\u3000\u5ee3\u7530\u3000\u65b0\u6d77\u3000\u67f4\u7530\u3000\u5927\u7530\u3000\u897f\u5ddd\u3000\u78ef\u8c9d\u3000\u6749\u5c71\u3000\u77f3\u4e95\u3001\u3000\u65b0\u898f\u306aVEGF\/PDGF\u69d8\u56e0\u5b50\u3001\u3000\u7279\u98582000-122994
\n(4)\u3000\u5927\u7530\u3000\u897f\u5ddd\u3000\u78ef\u8c9d\u3000\u6797\u3000\u77f3\u4e95\u3000\u6cb3\u5408\u3000\u82e5\u677e\u3000\u6749\u5c71\u3000\u6c38\u4e95\u3000\u5c0f\u5cf6\u3000\u5927\u69fb\u3000\u53e4\u9591\u3001\u3000\u5168\u9577cDNA\u5408\u6210\u7528\u30d7\u30e9\u30a4\u30de\u30fc\u304a\u3088\u3073\u305d\u306e\u7528\u9014\u3001\u3000\u7279\u98582000-253172
\n(5)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6cb3\u5408\u3000\u6749\u5c71\u3000\u6797\u3001\u3000\u5206\u6ccc\u30bf\u30f3\u30d1\u30af\u8cea\u307e\u305f\u306f\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u3000\u7279\u98582000-253173
\n(6)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3001\u3000\u5168\u9577cDNA\u5408\u6210\u7528\u30d7\u30e9\u30a4\u30de\u30fc\u304a\u3088\u3073\u305d\u306e\u7528\u9014\u3001\u3000\u7279\u98582000-280990
\n(7)\u3000\u5c0f\u7530\u3000\u6751\u677e\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3001\u3000\u65b0\u898f\u306a\u30d2\u30c8SH2\u86cb\u767d\u8cea\u3001\u3000\u7279\u98582000-196309
\n(8)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u8239\u6a4b\u3000\u5bae\u7530\u3001\u3000\u5e73\u6ed1\u7b4b\u7d30\u80de\u5206\u5316\u7dad\u6301\u306b\u95a2\u4e0e\u3059\u308b\u65b0\u898f\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514107
\n(9)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u8239\u6a4b\u3000\u59b9\u5c3e\u3000\u6839\u6d25\u3001\u3000\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bc\u30fb\u30d7\u30ed\u30c6\u30a4\u30f3\u30d5\u30a9\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514137
\n(10)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u8239\u6a4b\u3000\u59b9\u5c3e\u3000\u6839\u6d25\u3001\u3000\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bc\u30fb\u30d7\u30ed\u30c6\u30a4\u30f3\u30d5\u30a9\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\u3092\u30b3\u30fc\u30c9\u3059\u308b\u65b0\u898f\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514108
\n(11)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u6cb9\u8c37\u3000\u5150\u7389\u3000\u7dd1\u5ddd\u3001\u3000\u80c3\u764c\u95a2\u9023\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514109
\n(12)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u6cb9\u8c37\u3000\u5150\u7389\u3000\u7b46\u5b9d\u3000\u8c37\u53e3\u3001\u3000\u809d\u764c\u95a2\u9023\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514110\u3000PCT\/JP00\/05064
\n(13)\u3000\u5927\u7530\u3000\u78ef\u8c9d\u3000\u897f\u5ddd\u3000\u6797\u3000\u658e\u85e4\u3000\u5c71\u672c\u3000\u77f3\u4e95\u3000\u6749\u5c71\u3000\u82e5\u677e\u3000\u6c38\u4e95\u3000\u5927\u69fb\u3000\u5c71\u7530\u3000\u685c\u7530\u3000\u5927\u6797\u3001\u3000\u30d2\u30c8\u80ce\u5150\u5fc3\u7b4b\u7279\u7570\u7684\u767a\u73fe\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-514111\u3000PCT\/JP00\/05065
\n(14)\u3000\u677e\u672c\u3000\u5c0f\u7530\u3000\u658e\u85e4\u3000\u68ee\u5ddd\u3000\u5409\u7530\u3000\u8acf\u8a2a\u3000\u6749\u5c71\u3000\u5cb8\u672c\u3000\u795e\u5d0e\u3000\u4fdd\u7530\u3000\u4e95\u4e0a\u3001\u3000\u65b0\u898f\u306a\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\u7d50\u5408\u86cb\u767d\u8cea\u5171\u5f79\u578b\u306e\u53d7\u5bb9\u4f53\u304a\u3088\u3073\u305d\u308c\u3089\u306e\u907a\u4f1d\u5b50\u3001\u4e26\u3073\u306b\u305d\u308c\u3089\u306e\u88fd\u9020\u304a\u3088\u3073\u7528\u9014\u3001\u3000PCT\/JP00\/09408
\n(15)\u3000\u677e\u672c\u3000\u5c0f\u7530\u3000\u658e\u85e4\u3000\u68ee\u5ddd\u3000\u5409\u7530\u3000\u8acf\u8a2a\u3000\u6749\u5c71\u3001\u3000\u65b0\u898f\u306a\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\u7d50\u5408\u86cb\u767d\u8cea\u5171\u5f79\u578b\u306e\u53d7\u5bb9\u4f53\u304a\u3088\u3073\u305d\u308c\u3089\u306e\u907a\u4f1d\u5b50\u3001\u4e26\u3073\u306b\u305d\u308c\u3089\u306e\u88fd\u9020\u304a\u3088\u3073\u7528\u9014\u3001\u3000PCT\/JP00\/09409
\n(16)\u3000\u677e\u672c\u3000\u5c0f\u7530\u3000\u658e\u85e4\u3000\u68ee\u5ddd\u3000\u5409\u7530\u3000\u8acf\u8a2a\u3000\u6749\u5c71\u3001\u3000\u65b0\u898f\u306a\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\u7d50\u5408\u86cb\u767d\u8cea\u5171\u5f79\u578b\u306e\u53d7\u5bb9\u4f53GPRv53\u304a\u3088\u3073\u305d\u306e\u907a\u4f1d\u5b50\u3001\u4e26\u3073\u306b\u305d\u308c\u3089\u306e\u88fd\u9020\u304a\u3088\u3073\u7528\u9014\u3001\u3000PCT\/JP01\/02767
\n(17)\u3000\u897f\u5ddd\u3000\u6751\u4e0a\u3000\u539f\u7530\u3000\u78ef\u8c9d\u3000\u5927\u7530\u3000\u6749\u5c71\u3000\u6c38\u4e95\u3001\u3000\u907a\u4f1d\u5b50\u914d\u5217\u8868\u73fe\u30b7\u30b9\u30c6\u30e0\u53ca\u3073\u8a18\u9332\u5a92\u4f53\u3001\u3000\u7279\u98582000-325354
\n(18)\u3000\u698a\u539f\u3000\u95a2\u6839\u3000\u4f50\u85e4\u3000\u4e2d\u5ddd\u3000\u82e5\u677e\u3000\u6749\u5c71\u3000\u5165\u6c5f\u3000\u78ef\u8c9d\u3000\u6c38\u4e95\u3001\u3000\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u5897\u6b96\u56e0\u5b50\u7d50\u5408\u86cb\u767d\u8cea\u3001\u3000\u7279\u98582001-14766
\n(19)\u3000\u6749\u5c71\u3000\u68ee\u5ddd\u3000\u82e5\u677e\u3000\u5c0f\u7530\u3000\u5165\u6c5f\u3000\u78ef\u8c9d\u3000\u5897\u4fdd\u3001\u3000\u65b0\u898f\u306a\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\u7d50\u5408\u86cb\u767d\u8cea\u5171\u5f79\u578b\u306e\u53d7\u5bb9\u4f53PLACE6002312\u304a\u3088\u3073\u305d\u306e\u907a\u4f1d\u5b50\u3001\u4e26\u3073\u306b\u305d\u308c\u3089\u306e\u88fd\u9020\u304a\u3088\u3073\u7528\u9014\u3001\u3000\u7279\u98582001-127836
\n(20)\u3000\u6749\u5c71\u3000\u78ef\u8c9d\u3001\u3000\u8ee2\u5199\u8abf\u7bc0\u9818\u57df\u306e\u89e3\u6790\u65b9\u6cd5\u3001\u3000\u7279\u98582001-163400
\n(21)\u3000\u82e5\u5c3e\uff08\u5b8f\uff09\u3000\u82e5\u5c3e\uff08\u308a\u304b\uff09\u3000\u6749\u5c71\u3001\u3000\u30ec\u30d7\u30c1\u30f3\u8a98\u5c0e\u907a\u4f1d\u5b50\u3001\u3000\u7279\u98582001-174908
\n(22)\u3000\u78ef\u8c9d\u3000\u6749\u5c71\u3000\u5927\u69fb\u3000\u82e5\u677e\u3000\u4f50\u85e4\u3000\u77f3\u4e95\u3000\u5c71\u672c\u3000\u4e94\u5341\u91ce\u3000\u80a5\u5c3e\u3000\u658e\u85e4\u3000\u6c38\u4e95\u3000\u5165\u6c5f\u3000\u70ba\u8fd1\u3000\u95a2\u3000\u5409\u5ddd\u3000\u5927\u585a\u3000\u9577\u5f35\u3000\u5897\u4fdd\u3001\u3000\u65b0\u898f\u306a\u5168\u9577cDNA\u3001\u3000\u7279\u98582001-328381
\n(23)\u3000\u78ef\u8c9d\u3000\u6749\u5c71\u3000\u5927\u69fb\u3000\u82e5\u677e\u3000\u4f50\u85e4\u3000\u77f3\u4e95\u3000\u5c71\u672c\u3000\u4e94\u5341\u91ce\u3000\u80a5\u5c3e\u3000\u658e\u85e4\u3000\u6c38\u4e95\u3000\u5165\u6c5f\u3000\u70ba\u8fd1\u3000\u95a2\u3000\u5409\u5ddd\u3000\u5927\u585a\u3000\u9577\u5f35\u3000\u5897\u4fdd\u3001\u3000\u65b0\u898f\u306a\u5168\u9577cDNA\u3001\u3000\u7279\u98582001-379298
\n(24)\u3000\u78ef\u8c9d\u3000\u6749\u5c71\u3000\u5927\u69fb\u3000\u82e5\u677e\u3000\u4f50\u85e4\u3000\u77f3\u4e95\u3000\u5c71\u672c\u3000\u4e94\u5341\u91ce\u3000\u80a5\u5c3e\u3000\u658e\u85e4\u3000\u6c38\u4e95\u3000\u5165\u6c5f\u3000\u70ba\u8fd1\u3000\u95a2\u3000\u5409\u5ddd\u3000\u5927\u585a\u3000\u9577\u5f35\u3000\u5897\u4fdd\u3001\u3000\u65b0\u898f\u306a\u5168\u9577cDNA\u3001\u3000\u7279\u98582001-335833
\n(25)\u3000\u6749\u5c71\u3000\u6749\u5c71\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u9084\u5143\u80fd\u3092\u6709\u3059\u308b\u65b0\u898f\u5fae\u751f\u7269\u53ca\u3073\u3053\u308c\u3092\u7528\u3044\u305f\u74b0\u5883\u6d44\u5316\u6cd5\u3001\u3000\u7279\u98582005-211588\u3000\u7279\u8a31\u7b2c4395870\u53f7
\n(26)\u3000\u6749\u5c71\u3000\u521d\u91ce\u3000\u5c0f\u6797\u3001\u3000\u516d\u4fa1\u30af\u30ed\u30e0\u306e\u6d44\u5316\u5264\u304a\u3088\u3073\u516d\u4fa1\u30af\u30ed\u30e0\u542b\u6709\u7269\u306e\u516d\u4fa1\u30af\u30ed\u30e0\u6d44\u5316\u65b9\u6cd5\u3001\u3000\u7279\u98582010-280440\u3000\u7279\u8a31\u7b2c4807709\u53f7
\n(27)\u3000\u5927\u539f\u3001\u85e4\u6fa4\u3001\u7b20\u4e95\u3001\u4e80\u7530\u3001\u6749\u5c71\u3001\u571f\u4e95\u3000\u7570\u5e38\u8840\u7ba1\u691c\u51fa\u30b7\u30b9\u30c6\u30e0\u3001\u7570\u5e38\u8840\u7ba1\u691c\u51fa\u65b9\u6cd5\u3001\u53ca\u3073\u7570\u5e38\u8840\u7ba1\u691c\u51fa\u30d7\u30ed\u30b0\u30e9\u30e0\u3000\u7279\u98582024-44217<\/p>\n","protected":false},"excerpt":{"rendered":"

Scientific meetings 2026\u5e74 (1) \u6749\u5c71\u53cb\u5eb7\u3089\u3000\u6a5f\u68b0\u5b66\u7fd2\u3092\u5fdc\u7528\u3057\u305f\u4e73\u764c\u6bdb\u7d30\u8840\u7ba1\u306e\u5f62\u614b\u691c\u51fa\u6cd5\u306e\u958b\u767a\u3000\u7b2c8\u56de\u65e5\u672c\u30e1\u30c7\u30a3\u30ab\u30ebAI\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a (2) \u77f3\u5ddd\u885b\u3089\u3000\u7d50\u8178\u304c\u3093\u7d30\u80de\u306e\u7d30\u80de\u5206\u88c2\u6291\u5236\u6d3b\u6027\u3092\u6307\u6a19\u306b\u3057\u305f … <\/p>\n

“\u7814\u7a76\u696d\u7e3e” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11"}],"version-history":[{"count":70,"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":1518,"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/pages\/11\/revisions\/1518"}],"wp:attachment":[{"href":"https:\/\/sugiyama-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}